Postgraduate Specialization in Pediatrics, Postgraduate Specialization in Clinical Biochemistry
Full Professor in Clinical Biochemistry and Clinical Molecular Biochemistry at the Department of Experimental Medicine and Surgery, University of Rome Tor Vergata.
Director of the Postgraduate Specialization in Clinical Pathology and Clinical Biochemistry University of Rome Tor Vergata.
Director of the Inter Dipartimental Center for Culture and Science of Sport, University of Tor Vergata. And Dean of the Degree in of Sport and Exercise Sciences, University of Tor Vergata.
Head physician of the Clinical Biochemistry and Laboratory Emergency Units
From 1984 to 1991 my research focused on paediatric endocrinology with particular interest in growth hormone and insulin like growth factors and their binding proteins. From 1991 to 1998 my studies concentrated on the role of the molecules described above and on retinoids in the apoptotic pathways in oncology, in particular neuroblastoma.
Since 1998 I have focused on Glutathione transferases, a family of enzymes involved in cell detoxification and in the control of the programmed cell death. This work has concentrated on the role of those enzymes in the mechanisms responsible for drug resistance depending on changes in the redox status of the cell. As part of this research I have set up and managed a cell and molecular biology laboratory able to perform qRT-PCR and microarray for differential gene expression as well as some applications in Proteomics.
Since 2003 I have collaborated in the application of molecular biology methods and proteomics techniques in research applied to neurodegenerative diseases, oncology and pharmacogenetics.
Since 2009 I have collaborated in the application of molecular biology and biochemical methods (NMR) to monitoring of sport training and performance. He is author of more than 200 publications in International Journals.
President of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) Secretary of the International Federation Clinical Chemistry and Laboratory Medicine (IFCC)